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Meeting Program
Continuing Medical Education (CME) is jointly provided by
the American Association for Cancer Research (AACR) and the
Association of American Cancer Institutes (AACI)
All sessions will be held in the Wright Ballroom, Lobby Level, except where indicated.
Sunday, September 30
8:00-10:00 am

Corporate Roundtable Meeting (closed meeting)

11:00 am

Meeting Registration Begins
Wright Foyer, Lobby Level

11:00 am

Exhibits Open
Wright Foyer, Lobby Level

General Session

12:00 pm

Welcome and AACI Business Meeting

President’s Report
Dr. Stanton L. Gerson
Case Comprehensive Cancer Center

Executive Director’s Report
Ms. Barbara Duffy Stewart
Association of American Cancer Institutes

Treasurer’s Report
Mr. Jeff Walker
City of Hope National Medical Center

Program Chair’s Report
Dr. Randall F. Holcombe
University of Hawai'i Cancer Center
University of Hawai'i at Mānoa

CCAF Report
Mr. David M. Gosky
UK Markey Cancer Center

1:00 pm

A 10-Year Outlook for Academic Cancer Centers
Academic cancer centers have made remarkable strides in recent years that have enhanced their ability to deliver better care to patients, from the increased availability of genomic information sequencing to advances in the areas of targeted therapy, immunotherapy, and cancer screening technology. To help centers sustain that progress and build on their decades of learning, speakers in this session will share their perspectives and predictions for how academic cancer centers will evolve over the next 10 years. Topics of conversation will include maintaining research and managing innovation; distributed care; changes in reimbursement and points of care; and use of electronic methods of care delivery.

Moderator: Dr. Stanton L. Gerson
Case Comprehensive Cancer Center

Dr. Candace S. Johnson
Roswell Park Comprehensive Cancer Center

Dr. Michael B. Kastan
Duke Cancer Institute
Duke University Medical Center

Dr. Steven T. Rosen
City of Hope Comprehensive Cancer Center

2:00 pm

New President's Initiative
Dr. Roy A. Jensen
The University of Kansas Cancer Center

2:15 pm

Networking Break

2:45 pm

Cancer is a Global Issue: Partnerships with the Developing World
A growing number of cancer centers have established partnerships with countries in the developing world, with involvement extending to both research and the direct delivery of care. This session will include an overview of cancer research and treatment in the developing world, as well as details about how centers are interacting with specific countries including Kenya, Malawi, and Cuba, where US sanctions are creating unique challenges for cancer research collaborations.

Moderator: Dr. Malcolm Moore
BC Cancer (British Columbia, Canada)

Dr. Jack Welch
National Cancer Institute

Dr. Satish Gopal
UNC Lineberger Comprehensive Cancer Center
University of North Carolina at Chapel Hill

Dr. Dan Namarika
Ministry of Health, Malawi

Dr. Patrick J. Loehrer
Indiana University Melvin and Bren Simon Cancer Center

Dr. Kelvin P. Lee
Roswell Park Comprehensive Cancer Center

4:00-6:00 pm

6th Annual AACI Physician Clinical Leadership Initiative Meeting
Avoiding Physician Burnout: Strategies for Promoting Personal and Professional Satisfaction
Whether diagnosing cancer or managing related complications, devising personalized treatment plans, providing critical support in the face of daunting illness, or myriad other intellectually and emotionally stimulating tasks, caring for cancer patients can be immensely rewarding. Despite its rewards, caring for cancer patients can also be a stressful calling. From life and death decision-making to keeping pace with constantly evolving science, productivity requirements, and regulatory and administrative burdens, oncology practice takes its toll physically and emotionally. In this session, panelists will discuss the professional and personal consequences associated with physician burnout and will suggest strategies for avoiding downturns and promoting personal and professional satisfaction.

Moderator: Dr. Randall F. Holcombe
University of Hawai'i Cancer Center
University of Hawai'i at Mānoa

Dr. Fay J. Hlubocky
The University of Chicago Medicine Comprehensive Cancer Center

Dr. Daniel McFarland
Memorial Sloan Kettering Cancer Center

Dr. Ronald M. Epstein
Wilmot Cancer Institute
University of Rochester Medical Center

4:30-5:30 pm

CCAF Business Meeting
(closed session for members of CCAF)
Sullivan Ballroom A, Lobby Level

6:00-7:30 pm

Welcome Reception - Sponsored by Forte
Garden Terrace, Third Floor

Monday, October 1
7:00 am

General Breakfast
Sullivan Ballroom BC, Lobby Level

7:00 am

Exhibits Open
Wright Foyer, Lobby Level

8:00 am

AACI Presidential Initiative Update: Network Care
Managing cancer center networks is a complex task involving many moving parts; without a clear roadmap, a network can become unmanageable. AACI’s Network Care Initiative aims to help AACI’s academic cancer centers paint an accurate picture of their impact on cancer care across the regions they serve. AACI President Dr. Stanton Gerson will provide an update on the initiative, including a summary of final survey results. This session will cover topics related to network management, including standardization of care and the use of care paths (suggested diagnostic and treatment pathways); collaborating with other centers and community sites; working with varied employment network models; and providing access to clinical trials.

Moderator:Dr. Stanton L. Gerson
Case Comprehensive Cancer Center

Dr. Michael E. Kupferman
University of Texas MD Anderson Cancer Center

Dr. Ravi Salgia
City of Hope Comprehensive Cancer Center

8:45 am

How to Get the Most Out of Your EAB (concurrent)
When immersed in the day-to-day challenges of managing a cancer center, it can be easy to develop tunnel vision and lose sight of the big picture. A fresh perspective can help identify areas for improvement that may have been overlooked. As part of the Cancer Center Support Grant (CCSG) renewal process, NCI-Designated Cancer Centers are required to host site visits and demonstrate success in carrying out meritorious science. To prepare for renewal, cancer centers invite external advisory boards (EAB) to visit their cancer centers and provide detailed critiques. In this session, panelists will discuss best practices for selecting and inviting experts to join a cancer center's EAB, how to set expectations before a site visit, and the unique ways AACI cancer centers utilize this essential resource.

Moderator: Mr. Peter Connor
University of Wisconsin Carbone Cancer Center

Mr. David M. Gosky
UK Markey Cancer Center

Ms. Lauren Hackett
Vanderbilt-Ingram Cancer Center

Dr. Karen Knudsen
Sidney Kimmel Cancer Center at Jefferson Health

Dr. Michelle M. Le Beau
The University of Chicago Medicine Comprehensive Cancer Center

8:45 am

Big Data in Cancer Care (concurrent)
Sullivan Ballroom, Lobby Level
As Big Data changes the face of cancer research and treatment, the vast amount of information—and wide variety of sources for that information—are presenting significant challenges in collecting and integrating data. This session convenes commercial and academic players in the Big Data arena with an eye toward enhancing dialogue and developing stronger linkages that could lead to expanded information-sharing and improved patient care.

Moderator: Dr. Thomas A. Sellers
Moffitt Cancer Center

Dr. Kerin Adelson
Yale Cancer Center
Yale School of Medicine

Dr. John Sweetenham
Huntsman Cancer Institute
University of Utah

Ms. Cindy Terrano
Moffitt Cancer Center

10:00 am

Break

10:15 am

Cancer Health Economics
In the face of persistent shifts in the political landscape and health care marketplace, cancer centers are confronting an expanding array of funding and reimbursement challenges. Speakers in this session will discuss emergent issues such as understanding policies governing coverage for gathering genomic sequencing data and other innovative therapies, caring for underserved patients, and the latest developments at the Centers for Medicare and Medicaid Services.

Moderator: Dr. Randall F. Holcombe
University of Hawai'i Cancer Center
University of Hawai'i at Mānoa

Dr. Rena M. Conti
Boston University Questrom School of Business

Dr. Stuart Peacock
BC Cancer (British Columbia, Canada)

Dr. K. Robin Yabroff
American Cancer Society

11:30 am

Distinguished Scientist Award Presentation

Quantitative Medicine for Breast Cancer Patients

Charles M. Perou, PhD, a renowned breast cancer researcher at the UNC Lineberger Comprehensive Cancer Center, is being recognized by AACI for his accomplishments in the field of precision medicine and for groundbreaking research in the characterization of the diversity of human tumors. The clinical value of his work leading to the discovery of the intrinsic subtypes of breast cancer has had a profound impact on the treatment of breast cancer patients worldwide. Dr. Perou’s talk will focus on sequencing studies for gene expression analysis; specifically, on research results showing the value of sequencing-based approaches in breast and lung cancers.

Dr. Charles M. Perou
UNC Lineberger Comprehensive Cancer Center
University of North Carolina at Chapel Hill

12:30 pm

AACI Awards Lunch
Sullivan Ballroom, Lobby Level

2018 Champion for Cures Award
Richard and Susan Rogel

1:30 pm

Networking, CRI Posters, and Dessert - Sponsored by Florence
Wright Foyer, Lobby Level

2:00 pm

2018 Election Update
(Session not CME Credited)
With the 2018 Election just weeks away, Mr. Frommer will discuss the midterm elections highlighting retirements and toss-ups and the impact the winners might have on cancer centers. He will also discuss the prospects for funding for the NIH in this and the next Congress.

Mr. Ross A. Frommer
Columbia University Irving Medical Center

2:15 pm

AACI Clinical Research Initiative (CRI) Update
In July, AACI's Clinical Research Initiative (CRI) convened its 10th annual meeting with the program theme "Leveraging Change to Advance Cures for Cancer Patients." The meeting provided an opportunity for clinical trials office (CTO) administrative and medical directors, representatives from industry, corporate roundtable members, and others to network, share best practices, and begin conversations that can lead to more effective cancer treatments. During this session, Dr. Lee will highlight CRI's progress and growth over the past year—this year's meeting drew a record 405 attendees and more than 60 poster submissions—as well as goals for 2019. She will also present preliminary results from the CRI benchmarking survey, which captured data on CTO workload, structure and staffing, trial activation timeline, and sources of CTO funding support at AACI cancer centers.

Dr. Carrie Lee
UNC Lineberger Comprehensive Cancer Center
University of North Carolina at Chapel Hill

2:45 pm

Comprehensive Cancer Patient Support
Just as a spouse, children, relatives, and friends offer invaluable support to a loved one with cancer, cancer centers are increasingly recognizing the value to patients of a support network of experts drawn from fields as disparate as mental health, geriatric care, pain and symptom management, survivorship, and counseling for financially challenged patients. Over time, the field has transformed from palliative care and alternative medicine to an expansive array of research interests and treatment approaches that underpin nearly all cancer center operations. Panelists will explore programs that cancer centers have developed to enhance comprehensive support and deliver multidisciplinary care for the patient with cancer.

Moderator: Dr. Donald L. Rosenstein
UNC Lineberger Comprehensive Cancer Center
University of North Carolina at Chapel Hill

Dr. Smita Bhatia
UAB Comprehensive Cancer Center
University of Alabama at Birmingham

Dr. Judith A. Paice
The Robert H. Lurie Comprehensive Cancer Center
Northwestern University

Dr. Steven R. Patierno
Duke Cancer Institute
Duke University Medical Center

4:00 pm

Break

4:15 pm

CCSG Nuts and Bolts (concurrent)
Optimal compliance with NCI Cancer Center Support Grant (CCSG) guidelines will be explored in this session, with particular focus on selected cancer centers that have recently completed core grant submissions. The practical implications of preparing a CCSG competing renewal will be reviewed, and advice will be offered regarding different approaches for freestanding versus matrix cancer centers.

Moderator: Mr. Alex Zafirovski
The Robert H. Lurie Comprehensive Cancer Center
Northwestern University

Ms. Melissa Fitzmaurice Neligan
UCLA Jonsson Comprehensive Cancer Center

Mr. Dale Henry
Roswell Park Comprehensive Cancer Center

Ms. Donna Berrier
Hollings Cancer Center
Medical University of South Carolina

4:15 pm

Tumor Microenvironment (concurrent)
Sullivan Ballroom, Lobby Level
The tumor microenvironment is a complex network of cells and extracellular matrix proteins that support tumor development and progression. As we move toward personalized medicine in cancer care, understanding the influence of structural entities on gene expression and communication among functionally distinct, but phenotypically identical, cells within the environment is essential to effectively translating individualized therapy to patients. This session will focus on the impact of matrix rigidity on gene expression by the multiplicity of cells in the tumor microenvironment. The session will also highlight the impact of single cell genomics and transcriptomics and its potential to impact patient care.

Moderator: Dr. B. Mark Evers
UK Markey Cancer Center

Dr. Sufi Thomas
The University of Kansas Medical Center

Dr. Paul Robson
The Jackson Laboratory Cancer Center

5:30 pm

Sessions End

8:30-11:00 pm

Hospitality Suite - Sponsored by Complion
ETA Restaurant, Lobby Level

Tuesday, October 2
7:00 am

General Breakfast
Sullivan Ballroom BC, Lobby Level

7:00 am

Topic Specific Breakfast Roundtable Discussions
Sullivan Ballroom A, Lobby Level

Advice For Your First CCSG
Ms. Seanne Falconer
Masonic Cancer Center
University of Minnesota

Career Enhancement
Mr. Alex Zafirovski
The Robert H. Lurie Comprehensive Cancer Center
Northwestern University

Dr. John Crispino
The Robert H. Lurie Comprehensive Cancer Center
Northwestern University

Data Collection for Community Outreach and Engagement
Dr. Michael J. Bertram
UAB Comprehensive Cancer Center
University of Alabama at Birmingham

So You Want to be Designated?
Mr. David M. Gosky
UK Markey Cancer Center

Dr. Robert Mannel
Stephenson Cancer Center
University of Oklahoma

Introduction to the AACI Physician Clinical Leadership Initiative
Dr. Randall F. Holcombe
University of Hawai'i Cancer Center
University of Hawai'i at Mānoa

Follow-up on the CRI Benchmarking Survey
Ms. Janie Hofacker
Association of American Cancer Institutes

7:00 am

Exhibits Open
Wright Foyer, Lobby Level

General Session

8:00 am

NCI Director’s Report
The director of the National Cancer Institute (NCI) will highlight programmatic priorities and identify funding opportunities to support ongoing collaborations between the NCI and academic cancer centers.

Dr. Norman E. Sharpless
National Cancer Institute

8:45 am

Guidelines-Driven Review: Conveying Comprehensiveness, Training, and Community Engagement
As cancer centers continue to wrestle with revised guidelines for the NCI's CCSG application, some metrics that help to determine funding levels are proving problematic. Panelists will discuss comprehensiveness, training, and community engagement, with an eye toward clarifying definitions, NCI’s perspective and expectations, and factors that drive the scoring of centers’ performance in these areas.

Moderator: Dr. Roy A. Jensen
The University of Kansas Cancer Center

Dr. Michael Teitell
UCLA Jonsson Comprehensive Cancer Center

Dr. Cory Abate-Shen
Herbert Irving Comprehensive Cancer Center
Columbia University Medical Center

Dr. Randall F. Holcombe
University of Hawai'i Cancer Center
University of Hawai'i at Mānoa

9:45 am

Break

10:00 am

Best Practices in Cell Therapy/CAR T
The FDA granted its first approvals for CAR T-cell therapy in 2017. In these early days of cellular therapy and other forms of adoptive cell transfer, more cancer centers are stepping up their efforts in the field. Among the decisions being weighed are whether to develop cells in-house, procure them from commercial entities, or embrace a hybrid approach. Panelists will consider that issue as well as the nuts and bolts of developing a CAR T-cell therapy program, including intake and management issues, standard operating procedures, financial challenges, and regulatory requirements.

Moderator: Dr. Joseph McGuirk
The University of Kansas Cancer Center

Mr. Richard P. Bondi
UPMC Hillman Cancer Center

Dr. Lihua Elizabeth Budde
City of Hope Comprehensive Cancer Center

Dr. Stephan A. Grupp
Children's Hospital of Philadelphia

11:00 am

Update on the NCI Cancer Centers Program
This session provides an opportunity for an open dialogue with the director of the NCI Office of Cancer Centers about the requirements and funding of the Cancer Center Support Grant.

Dr. Henry P. Ciolino
National Cancer Institute

11:45 am

Adjourn

Program subject to change.


Continuing Medical Education

Joint Providership Statement
Jointly provided by the American Association for Cancer Research and the Association of American Cancer Institutes.

Accreditation
This activity has been planned and implemented in accordance with the accreditation requirements and policies of the Accreditation Council for Continuing Medical Education (ACCME) through the joint providership of the American Association for Cancer Research and the Association of American Cancer Institutes. The American Association for Cancer Research is accredited by the ACCME to provide continuing medical education for physicians.

Credit Designation
The American Association for Cancer Research designates this live activity for a maximum of 15.25 AMA PRA Category 1 Credit(s)™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Credit certification for individual sessions may vary, dependent upon compliance with the ACCME Accreditation Criteria. The final number of credits may vary from the maximum number indicated above.

Claiming (CME) Credit
Physicians and other health care professionals seeking AMA PRA Category 1 Credit(s)™ for this live continuing medical education activity must complete the CME Request for Credit Survey by November 5, 2018. Certificates will only be issued to those who complete the survey. Your CME certificate will be sent to you via email after the completion of the activity.

Learning Objectives
Physicians and other health care professionals who attend the meeting should be able to summarize the program content, discuss its application in clinical practice, and convey the information to administrators at their centers. As part of the program's learning objectives, all attendees should be able to describe and discuss:

• The evolution of the academic cancer center in the next decade.
• The value of bi-directional partnerships from both the clinical and research perspective in the global cancer enterprise.
• Strategies for promoting both the clinical and research perspective in the global cancer enterprise.
• Models of care across cancer center networks which promote efforts to integrate treatment services into the community.
• Best practices for assembling an external advisory board (EAB)
• Ways to collect and integrate data with an eye toward expanded information- sharing and improved care for the cancer patient.
• Strategies for navigating the changing health care marketplace.
• The value of sequencing based approaches in breast and lung cancers.
• Progress of the AACI Clinical Research Initiative (CRI) over the last decade.
• Programmatic models which enhance comprehensive patient support and care.
• Compliance with the most current NCI CCSG guidelines.
• The impact of matrix rigidity on gene expression by the multiplicity of cells in the tumor microenvironment.
• Challenges and opportunities for collaboration between academia, government, and the private sector.
• Various aspects of compliance with the NCI CCSG guidelines with a focus on comprehensiveness, training, and community engagement.
• Developing a CAR T-cell therapy program with an emphasis on intake and management issues, standard operating procedures, and regulatory requirements.
• NCI's priorities, policies, strategies and goals for the national cancer research enterprise, and their relationship to academic cancer centers.

Americans with Disabilities Act
It is the policy of the American Association for Cancer Research and the Association of American Cancer Institutes not to discriminate against any person on the basis of disabilities. If you feel you need services or auxiliary aids mentioned in this act in order to fully participate in this continuing education activity, please contact 412-647-6111 or attach a note to your registration form.

Faculty Disclosure
It is the policy of the American Association for Cancer Research and the Association of American Cancer Institutes to require disclosure of financial relationships from individuals in a position to control the content of a CME activity; to identify and resolve conflicts of interest related to those relationships; and to make disclosure information available to the audience prior to the CME activity. Presenters are required to disclose discussions of unlabeled/unapproved uses of drugs or devices during their presentations.

Target Audience
This transdisciplinary conference is designed for basic and clinical scientists, as well as for physician-scientists from academia, industry, government, and other institutions with interest in innovative systems and technologies for diagnosing, preventing, and treating cancer and its long-term effects. All attendees have a significant impact on cancer research and patient care.

Attendees may include:
• Leaders of AACI's academic and freestanding cancer research centers, including cancer center directors, executive administrators, and other top scientific and clinical staff
• Leaders from industry and government agencies as well as those of cancer research and advocacy organizations
• Medical professionals, including oncologists, pharmacists, radiologists, nuclear medicine physicians, nurses, and psychologists
• Social workers, cancer communication specialists, public health leaders, and faculty members who focus on cancer